Potential use of the stinging nettle as an enhancer of weight gain and innate immune response in broiler chickens

Main Article Content

Carmen Dana ŞANDRU Mihaela NICULAE Emoke PALL Aurel VASIU Florinel BRUDASCA Marina SPÎNU


Researches were conducted to investigate the in vivo effect of an nettle plant alcohol extract on the phagocytosis and body weight in 48 days old broiler chickens (n=34). The birds were divided into three groups: subcutaneously injected with 0.5 ml of saline (control, n = 12), with 0.5 ml of alcohol (group II, n=11) or with 0.5 ml of alcoholic nettle extract (group III, n=11). Sterile heparinized blood, sampled on days 0, 7 and 13, was processed by an in vitro carbon particle inclusion test, the phagocytosis being expressed in optical density units. The birds were weighed simultaneously with the blood sampling. We concluded that a single nettle extract treatment does not significantly influence the phagocytosis, while the second administration intensified it. The alcoholic nettle extract had a beneficial effect on the body weight of broiler chickens.
Key words: Broiler chickens; Nettle extract; Phagocytosis; Body weight.

Article Details

How to Cite
ŞANDRU, Carmen Dana et al. Potential use of the stinging nettle as an enhancer of weight gain and innate immune response in broiler chickens. Stiinta agricola, [S.l.], n. 1, p. 119-122, july 2017. ISSN 2587-3202. Available at: <http://sa.uasm.md/index.php/sa/article/view/546>. Date accessed: 23 sep. 2017.
Table of contents


(1996). Modificări ale activităţii fagocitare şi sintezei de lizozim în urma administrării extractului de Calendula
officinalis la puii de găină. In: Actualităţi în patologia animalelor domestic: simp. 7-8 nov., Cluj, vol. XXII, p. 183.
2. FRANCIŠKOVIĆ, M., GONZALEZ-PÉREZ, R., ORČIĆ, D., SÁNCHEZ DE MEDINA, F., MARTÍNEZ-AUGUSTIN, O., SVIRČEV, E., SIMIN, N., MIMICA-DUKIĆ, N. (2017). Chemical Composition and Immuno-Modulatory Effects of Urtica dioica L. (Stinging Nettle) Extracts. In: Phytotherapy research. ISSN 0951-418X. DOI: 10.1002/ptr.5836. [Epub ahead of print].
3. GALELLI, A., TRUFFA-BACHI, P. (1993). Urtica dioica agglutinin, a superantigenic lectin from stinging nettle rhizome. In: Journal of Immunology, vol. 151(4), pp. 1821-1831. ISSN 1550-6606.
4. HARATA, K., SCHUBERT, W.D., MURAKI, M. (2001). Structure of Urtica agglutinin isolectin I: dimer formation mediated by two zinc ions bound at the sugar-binding site. In: Acta Crystallographica. Section D.
Biological Crystallography, vol. 57(Pt 11), pp. 1513-1517. ISSN 0907-4449.
5. IONESCU, Stoian St., SAVOPOL, E. (1977). Extracte farmaceutice vegetale. Bucureşti: Ed. Medicală. 495 p.
6. KARAKAYA, S., EL, S.N., TAS, A.A. (2001). Antioxidant Activity of some foods containing phenolic compounds. In: International Journal of Food Sciences and Nutrition, vol. 52(6), pp. 501-508. ISSN 0963-7486.
7. OBERTREIS, B., RUTTKOWSKI, T., TEUCHER, T., BEHNKE, B., SCHMITZ, H. (1996). Ex-vivo in-vitro
inhibition of lipopolysaccharide stimulated tumor necrosis factor-alpha and interleukin-1 beta secretion in human whole blood by extractum urticae dioicae foliorum. In: Arzneimittelforschung, vol. 46(4), pp. 389-394. Erratum in:
Arzneimittelforschung, vol. 46(9), p. 936. ISSN 0004-4172.
8. POP, M., SPÎNU, M., VASIU, C., RĂPUNTEAN, Gh., 1990, Elemente definitorii ale profilului imun la păsări crescute în sistem intensive. In: Rev. Rom. Med.Vet., nr. 1, pp. 55-61. ISSN 1220-3173.
9. PUSZTAI, A., EWEN, S.W., GRANT, G., BROWN, D.S., STEWART, J.C., PEUMANS, W.J., Van DAMME E.J., BARDOCZ, S. (1993). Antinutritive effects of wheat-germ agglutinin and other N-acetylglucosamine-specific
lectins. In: British Journal of Nutrition, vol. 70(1), pp. 313-321. ISSN 0007-1145.
10. RADU, I., ANDRONESCU, E. (1984). Vademecum fitoterapeutic. Bucureşti: Ed. Medicală. 287 p.
11. RANDALL, C., MEETHAN, K., RANDALL, H., DOBBS, F. (1999). Nettle sting of Urtica dioica for joint pain - an exploratory study of this complementary therapy. In: Complementary Therapies in Medicine, vol. 7(3),
pp. 126-131. ISSN 0965-2299.
12. SAFAMEHR, A., FALLAH, F., NOBAKHT, A. (2013). Growth Performance and Biochemical Parameters of Broiler Chickens on Diets Consist of Chicory (Cichorium intybus) and Nettle (Urtica dioica) with or without
Multi-Enzyme. In: Iranian Journal of Applied Animal Science, vol. 3(1), pp. 131-137. ISSN 2251-628X.
13. SAFAMEHR, A., MIRAHMADI, M., NOBAKHT, A. (2012). Effect of nettle (Urtica dioica) medicinal plant on growth performance, immune responses, and serum biochemical parameters of broiler chickens. In: International Research Journal of Applied & Basic Sciences, vol. 3(4), pp. 721-728. ISSN 2251-838X.
14. SPÎNU, M., BRUDAŞCĂ, F., DOBREAN, V., VASIU, A., OPRIŞ, A. (1998). Vegetal extract treatment influences the immunological profile in chicken. In: 5th International Veterinary Immunology Symposium, Ludhiana, Punjab, India.
15. SPÎNU, M., DANCEA, Z., ŞEPŞI, R., BRUDAŞCĂ, Gh.F., OPREA, M., SPÎNU, O. (1992). Dinamica unor indicatori ai profilului imunologic la păsări supuse imunostimulării. In: Actualităţi în patologia animalelor domestice: simp., Cluj-Napoca, vol. XVIII, p. 157.
16. WANG, M., WEI, Y., SHIYAN, Z. (2001). Preliminary pharmacological study on polysaccharide from Urtica fissa. In: Zhong Yao Cai = Journal of Chinese Medicinal Materials, vol. 24 (9), pp. 666-7. ISSN 1001-4454

Most read articles by the same author(s)