Enhanced responses in antigen primed dogs after administration of a complex microbial immune stimulating compound

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Florinel BRUDASCA Carmen Dana SANDRU Constantin CERBU Aurel VASIU Marina SPINU


The research aimed to investigate the efficacy of antiparvoviral monovalent vaccine for puppies treated with a complex poly-bacterial compound. The experiment was carried out on 17 Labrador Retriever
puppies, from 41 to 63 days of age. The two groups (experimental and control) were subjected to: a) a polybacterial preparation and antiparvoviral vaccine (n = 12) and b) to antiparvoviral vaccine (n = 5), respectively. One ml of a poly-bacterial preparation was administered on days 0, 2, 4, 6, while the antiparvoviral vaccine Duramune KF11 was injected on day 8 of the experiment. Phagocytic activity and total lysozyme concentrations were measured on days 0, 8 and 22 of the experiment. The global immunostimulating effects of the poly-bacterial preparation on the innate immune system of vaccinated puppies increased when compared to those of the control variant.
Key words: Puppies; Vaccine; Poly-bacterial preparation; Immune indicators; Phagocytosis; Lysozyme.

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BRUDASCA, Florinel et al. Enhanced responses in antigen primed dogs after administration of a complex microbial immune stimulating compound. Stiinta agricola, [S.l.], n. 1, p. 114-118, july 2017. ISSN 2587-3202. Available at: <http://sa.uasm.md/index.php/sa/article/view/545>. Date accessed: 21 oct. 2018.
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